Rubella in Adult
Infection in the United States is rare, owing to widespread vaccination. There is a higher incidence in confined populations such as military bases and schools. The disease is more common in the spring and summer. Arthralgias and mild arthritis, splenomegaly, thrombocytopenia, and testicular pain are sometimes seen. Encephalitis occurs in 1 out of 6000 cases. Pain on lateral or upward eye movement is common in this disorder. Thrombocytopenic purpura is also a rare complication.
Even in the immunocompromised host, rubella is usually a benign illness. The major impact of rubella is on the fetus of a pregnant patient and is one of the TORCH (toxoplasmosis, other [syphilis, varicella zoster, parvovirus B19], rubella, cytomegalovirus, and herpes simplex) diseases. These disorders can cause fetal heart and eye malformations, cataracts, deafness, intellectual disability, thrombocytopenic purpura, hepatosplenomegaly, intrauterine growth retardation, interstitial pneumonia, myocarditis, myocardial necrosis, and metaphyseal bone lesions.
B06.9 – Rubella without complication
36653000 – Rubella
Differential Diagnosis & Pitfalls