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Schizophrenia spectrum disorders
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Schizophrenia spectrum disorders

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Contributors: Christine Osborne MD
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Synopsis

Schizophrenia spectrum disorder is a heterogeneous disorder characterized by disruptions of perception, language, thinking, social activity, volition, and affect. Schizophrenia typically begins in late adolescence with an insidious onset, progressing from social withdrawal and perceptual perturbations to paranoia, recurrent delusions, and hallucinations. Symptoms are described as positive or negative, and patients must demonstrate at least 2 of these for a 1-month period and continuous signs for at least 6 months to meet formal diagnostic criteria:
  • Positive symptoms – Conceptual disorganization, delusions, and hallucinations.
  • Negative symptoms – Loss of functioning in daily life, anhedonia, decreased emotional expression, diminished social engagement, and impaired concentration. Negative symptoms predominate in one third of patients with schizophrenia.
Risk factors for development of schizophrenia include winter birth, increasing parental age, and family history of schizophrenia. Schizophrenia is seen in 6.6% of all first-degree relatives of the affected patient and, if both parents are affected, the risk of schizophrenia in the offspring is 40%.

Codes

ICD10CM:
F20.9 – Schizophrenia, unspecified

SNOMEDCT:
58214004 – Schizophrenia

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Last Updated: 07/26/2017
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Schizophrenia spectrum disorders
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Schizophrenia spectrum disorders : Agitation, Anxiety, Delirium, Hallucination, Cognitive impairment, Delusions, Depression
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