Sebaceous hyperplasia in newborn
Sebaceous hyperplasia occurs in nearly half of term newborns with premature infants being less commonly affected.
L73.8 – Other specified follicular disorders
403852003 – Neonatal sebaceous gland hyperplasia
Differential Diagnosis & Pitfalls
- – The papules of milia are typically discrete, solitary, and whiter in color compared to sebaceous hyperplasia.
- Acne neonatorum – Follicular-based papules that may have patulous ostia (open comedones) or smooth papules (closed comedones).
- Nevus sebaceus – Agminated yellow, waxy papules, also composed of sebocytes, may occur on the face. These usually coalesce into a plaque.
- Micronodular juvenile xanthogranulomas – Multiple yellow or red-brown papules, typically lacking a follicular basis, and individually larger than sebaceous hyperplasia.
- Langerhans cell histiocytosis – Some variants of self-limited congenital histiocytosis may present with multiple red-brown papules.