Seborrheic dermatitis in Infant/Neonate
Infantile seborrheic dermatitis usually manifests in the second week of life and lasts 4-6 months. It has no racial / ethnic or sex predilection. It characteristically presents on the face, diaper area, and folds of the neck and axillae.
The pathophysiology of infantile seborrheic dermatitis is not well known. However, many factors have been postulated to influence its development. Maternal androgens, transferred to the baby in utero, are thought to result in overactive sebaceous gland activity. In addition, the yeast Malassezia has been implicated.
L21.9 – Seborrheic dermatitis, unspecified
50563003 – Seborrheic dermatitis
Differential Diagnosis & Pitfalls
Psoriasis is extremely uncommon in neonates and infants. However, familial and genetically determined forms of psoriasis and other psoriasiform dermatitis do characteristically present with infantile psoriasis involving a similar distribution. The scaling is thicker in nonoccluded areas and plaques are better defined.
When localized in the diaper area, dermatoses to consider besides irritant contact dermatitis:
- Psoriasis – consider in those with particularly difficult-to-remove scales; examine the patient in locations characteristic for psoriasis
- Allergic contact dermatitis
- Tinea cruris - rare in infancy
- Langerhans cell histiocytosis
- Kawasaki disease
- Sexual abuse
- Acrodermatitis enteropathica
- Lichen sclerosus
- Perianal streptococcal infection
- Congenital syphilis
Drug Reaction Data