Spermatoceles occur in males and are often present at birth or in infancy. In utero exposure to a synthetic estrogen, diethylstilbestrol, is a known risk for the development of a spermatocele. This risk was recognized in the 1970s and 1980s, and diethylstilbestrol is now recognized as a category X medication.
Spermatoceles do not progress into testicular cancer. They do not strangulate or increase risk of vascular compromise to the testicles or surrounding structures.
N43.40 – Spermatocele of epididymis, unspecified
49263001 – Spermatocele
Differential Diagnosis & Pitfalls