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Squamous cell carcinoma in situ - Hair and Scalp
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Squamous cell carcinoma in situ - Hair and Scalp

See also in: Overview
Contributors: Jeffrey M. Cohen MD, Roman Bronfenbrener MD, Sarah Hocker DO, Belinda Tan MD, PhD, Yevgeniy Balagula MD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Cutaneous squamous cell carcinoma in situ (SCCis), also known as Bowen disease, is defined histopathologically by malignant keratinocytes that involve the full thickness of the epidermis. This common malignancy is primarily seen in older adults and most frequently occurs on sun-exposed skin. The development of SCCis has also been associated with immunosuppression, chronic lymphocytic leukemia, radiation exposure, arsenic ingestion, and human papillomavirus (HPV). There is no sex predilection. It is frequently seen accompanying other stigmata of chronic sun damage, such as actinic keratoses, solar lentigines, and other keratinocytic carcinomas. If left untreated, SCCis can evolve into invasive SCC.

Related topic: Cutaneous squamous cell carcinoma

Codes

ICD10CM:
D04.9 – Carcinoma in situ of skin, unspecified

SNOMEDCT:
189565007 – Squamous cell carcinoma in situ

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Differential Diagnosis & Pitfalls

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Therapy

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Last Reviewed:12/12/2018
Last Updated:01/16/2019
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Squamous cell carcinoma in situ - Hair and Scalp
See also in: Overview
Squamous cell carcinoma in situ : Scaly plaque
Clinical image of Squamous cell carcinoma in situ
A well-demarcated, scaly, erythematous plaque on the dorsal finger.
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