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Squamous cell carcinoma in situ - Hair and Scalp
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Other Resources UpToDate PubMed

Squamous cell carcinoma in situ - Hair and Scalp

See also in: Overview
Contributors: Jeffrey M. Cohen MD, Roman Bronfenbrener MD, Sarah Hocker DO, Belinda Tan MD, PhD, Yevgeniy Balagula MD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Cutaneous squamous cell carcinoma in situ (SCCis), also known as Bowen disease, is defined histopathologically by malignant keratinocytes that involve the full thickness of the epidermis. This common malignancy is primarily seen in older adults and most frequently occurs on sun-exposed skin. The development of SCCis has also been associated with immunosuppression, chronic lymphocytic leukemia, radiation exposure, arsenic ingestion, and human papillomavirus (HPV). There is no sex predilection. It is frequently seen accompanying other stigmata of chronic sun damage, such as actinic keratoses, solar lentigines, and other keratinocytic carcinomas. If left untreated, SCCis can evolve into invasive SCC.

Related topic: Cutaneous squamous cell carcinoma

Codes

ICD10CM:
D04.9 – Carcinoma in situ of skin, unspecified

SNOMEDCT:
189565007 – Squamous cell carcinoma in situ

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

  • Superficial basal cell carcinoma
  • Cutaneous squamous cell carcinoma
  • Psoriasis
  • Actinic keratosis
  • Porokeratosis
  • Lichenoid keratosis
  • Seborrheic keratosis
  • Extramammary Paget disease
  • Tinea (eg, Tinea corporis, Tinea capitis)
  • Nummular dermatitis
  • Melanoma
  • Common wart
  • Lichen simplex chronicus
  • Discoid lupus erythematosus
  • Lichen planus

Best Tests

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Management Pearls

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Therapy

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References

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Last Reviewed:12/12/2018
Last Updated:01/16/2019
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Patient Information for Squamous cell carcinoma in situ - Hair and Scalp
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Squamous cell carcinoma in situ - Hair and Scalp
See also in: Overview
A medical illustration showing key findings of Squamous cell carcinoma in situ : Scaly plaque
Clinical image of Squamous cell carcinoma in situ - imageId=75121. Click to open in gallery.  caption: 'A well-demarcated, scaly, erythematous plaque on the dorsal finger.'
A well-demarcated, scaly, erythematous plaque on the dorsal finger.
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