Staphylococcal scalded skin syndrome in Child
Alerts and Notices
Synopsis

Codes
ICD10CM:L00 – Staphylococcal scalded skin syndrome
SNOMEDCT:
200946001 – Staphylococcal scalded skin syndrome
Look For
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Bullous impetigo – Localized with honey-colored crusted plaques, bacteria present in bullae.
- Toxic shock syndrome – High fevers and severe systemic symptoms including vomiting and diarrhea; hypotension quickly ensues; diffuse scarlatiniform exanthem that starts on the trunk (in contrast to face in SSSS).
- Sunburn
- Kawasaki disease – Fever lasting more than 5 days with oral mucosal changes, conjunctival injection, and cervical lymphadenopathy.
- Drug hypersensitivity syndrome (DRESS)
- Exanthematous drug eruption
- Drug-induced erythroderma
- Toxic epidermal necrolysis (TEN) – Drug induced, high fevers, skin tenderness, mucosal erosions, and skin detachment about 1-3 weeks after the inciting medication is started.
- Stevens-Johnson syndrome – Drug induced, high fevers, skin tenderness, mucosal erosions, and skin detachment about 1-3 weeks after the inciting medication is started.
- Scarlet fever – 1 mm erythematous papules, always elevated WBC with left shift, eosinophilia in up to 20% of patients.
- Erythrodermic psoriasis
- Atopic dermatitis
- Contact dermatitis
- Ichthyosis
- Lupus erythematosus
- Pemphigus erythematosus
- Pityriasis rubra pilaris
- Scabies
- Seborrheic dermatitis
- Lymphomas
- Urticaria
- Erysipelas
- Necrotizing fasciitis – Rapidly progressing necrosis of fascia and subcutaneous fat.
Best Tests
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Management Pearls
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Therapy
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References
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Last Reviewed:06/08/2017
Last Updated:01/10/2018
Last Updated:01/10/2018