Staphylococcal scalded skin syndrome in Child
L00 – Staphylococcal scalded skin syndrome
200946001 – Staphylococcal scalded skin syndrome
Differential Diagnosis & Pitfalls
- Bullous impetigo – Localized with honey-colored crusted plaques, bacteria present in bullae.
- Toxic shock syndrome – High fevers and severe systemic symptoms including vomiting and diarrhea; hypotension quickly ensues; diffuse scarlatiniform exanthem that starts on the trunk (in contrast to face in SSSS).
- Kawasaki disease – Fever lasting more than 5 days with oral mucosal changes, conjunctival injection, and cervical lymphadenopathy.
- Drug hypersensitivity syndrome (DRESS)
- Exanthematous drug eruption
- Drug-induced erythroderma
- Toxic epidermal necrolysis (TEN) – Drug induced, high fevers, skin tenderness, mucosal erosions, and skin detachment about 1-3 weeks after the inciting medication is started.
- Stevens-Johnson syndrome – Drug induced, high fevers, skin tenderness, mucosal erosions, and skin detachment about 1-3 weeks after the inciting medication is started.
- Scarlet fever – 1 mm erythematous papules, always elevated WBC with left shift, eosinophilia in up to 20% of patients.
- Erythrodermic psoriasis
- Atopic dermatitis
- Contact dermatitis
- Lupus erythematosus
- Pemphigus erythematosus
- Pityriasis rubra pilaris
- Seborrheic dermatitis
- Necrotizing fasciitis – Rapidly progressing necrosis of fascia and subcutaneous fat.