Syringomas are benign adnexal tumors derived from intraepidermal luminal cells of eccrine sweat ducts. They present as small, dome-shaped papules, often in a periorbital distribution. They may, however, occur at any site on the body. They are seen more frequently in women and in those with Down syndrome. Although usually sporadic, familial cases have been reported and inherited in an autosomal dominant manner. Treatment of these lesions is cosmetic.