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Trachoma
See also in: External and Internal Eye
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Trachoma

See also in: External and Internal Eye
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Synopsis

Trachoma, also known as granular conjunctivitis or Egyptian ophthalmia, is a bacterial infection of the eye caused by Chlamydia trachomatis serovars A, B, Ba, and C. The organism is found in eye secretions and spread by direct contact, contact with fomites (eg, clothing), and flies. Trachoma is predominately found in developing countries, particularly sub-Saharan Africa and Asia. The initial infection is frequently acquired before 2 years of age, and recurrent infection causes chronic inflammation with scarring of the cornea, which can lead to blindness if untreated. Worldwide, trachoma is the most preventable cause of infectious blindness.

Clinical manifestations of trachoma can be divided into 2 clinical phases: active trachoma and cicatricial disease.

Active trachoma – Active trachoma is mostly seen in young children and occurs after a 5-10 day incubation period from exposure. While most individuals are asymptomatic, signs and symptoms can include the following:
  • Swelling of the eyelids from formation of follicles on the superior tarsal conjunctiva
  • Eye irritation
  • Mucopurulent discharge
Cicatricial disease – The later stage of trachoma, known as cicatricial disease, is secondary to repeated episodes of infection and is mainly seen in adults. Clinical features include the following:
  • Marked conjunctival inflammation
  • Entropion – Conjunctival scarring leading to inward turning of the eyelid
  • Trichiasis – Ingrown eyelashes from entropion causing irritation of eyeball and cornea
  • Corneal edema, ulceration, and scarring due to trichiasis, resulting in corneal pannus (inflammatory vascular tissue) followed by corneal opacity, and eventually blindness

Codes

ICD10CM:
A71.9 – Trachoma, unspecified

SNOMEDCT:
2576002 – Trachoma

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

The important differential diagnoses are as follows:

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Therapy

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References

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Last Updated: 08/01/2014
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Trachoma
See also in: External and Internal Eye
Print 10 Images
View all Images (10)
(with subscription)
Trachoma (Active) : Eye pain, Blurred vision, Photophobia, Corneal diffuse white infiltrate, Eyelid edema, Preauricular lymphadenopathy, Eye discharge
Clinical image of Trachoma
Copyright © 2019 VisualDx®. All rights reserved.