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Transient neonatal pustular melanosis
Other Resources UpToDate PubMed

Transient neonatal pustular melanosis

Contributors: Craig N. Burkhart MD, Dean Morrell MD, Lowell A. Goldsmith MD, MPH
Other Resources UpToDate PubMed

Synopsis

Transient neonatal pustular melanosis (TNPM) is an idiopathic pustular disease of term newborns. Lesions begin in utero as pustules that then rupture, leaving behind collarettes of scale and hyperpigmented macules. Depending on the eruption's stage of evolution, infants are born with some combination of pustules, scale, and hyperpigmented macules. The pustules and scale resolve within 2 weeks of birth, leaving behind hyperpigmented macules that persist for several months. New lesions do not form after delivery.

Codes

ICD10CM:
P83.88 – Other specified conditions of integument specific to newborn

SNOMEDCT:
239092005 – Transient neonatal pustulosis

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Transient noninfectious vesiculopustular dermatoses:
Persistent noninfectious vesiculopustular dermatoses:
If mainly consisting of scale:
If mainly consisting of pigmented macules:
If there are many pustules:

Best Tests

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Management Pearls

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Therapy

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References

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Last Updated:02/07/2022
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Transient neonatal pustular melanosis
A medical illustration showing key findings of Transient neonatal pustular melanosis : Present at birth, Hyperpigmented macules
Clinical image of Transient neonatal pustular melanosis - imageId=119239. Click to open in gallery.  caption: 'A close-up of numerous small pustules.'
A close-up of numerous small pustules.
Copyright © 2022 VisualDx®. All rights reserved.