Traumatic eosinophilic granuloma - Oral Mucosal Lesion
The lesions occur over a wide age range.
Symptoms are often surprisingly mild, but patients may report tenderness depending on the size and location of the ulcer.
Reported range of duration is from 1 week to 8 months.
K13.4 – Granuloma and granuloma-like lesions of oral mucosa
8090002 – Eosinophilic granuloma of oral mucosa
- Behçet's syndrome
- Aphthous ulcer
- Drug-induced oral ulcer
- Oral traumatic ulcer – Generally the routine traumatic ulcer is not as chronic as the traumatic granuloma, although candidal infection of the periphery of a traumatic ulcer may cause it to persist.
- Squamous cell carcinoma – This malignancy may appear to be very similar clinically, and biopsy is often necessary to distinguish between these two entities.
- Non-Hodgkin's lymphoma – This malignancy, when secondarily ulcerated, can also appear clinically very similar to traumatic granuloma. Recent reports have suggested that a small percentage of lesions that may have been categorized as traumatic granuloma in the past could represent an indolent CD-30-positive T-cell lymphoma.
- Histoplasmosis or other deep fungal infection – Biopsy reveals Histoplasma capsulatum or other causative organisms in tissue sections stained with PAS or GMS method.
- Tuberculous ulcer – Biopsy shows necrotizing granulomatous inflammation and acid-fast bacilli.