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Trichodysplasia spinulosa
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Trichodysplasia spinulosa

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Contributors: Vivian Wong MD, PhD, Susan Burgin MD
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Synopsis

Trichodysplasia spinulosa is a rare viral infection seen in immunocompromised patients. It is caused by reactivation of trichodysplasia spinulosa-associated polyomavirus (TSPyV). Patients develop flesh-colored or erythematous follicular papules on the central face, alopecia, and facial disfigurement. Primary exposure to TSPyV occurs in early childhood, and most people become seropositive by adulthood. Infected individuals do not develop clinical manifestations unless in the setting of immunosuppression.

This condition was previously known as viral-associated trichodysplasia, cyclosporine-induced folliculodystrophy, pilomatrix dysplasia, and trichodysplasia of immunosuppression.

Codes

ICD10CM:
B34.9 – Viral infection, unspecified

SNOMEDCT:
21049007 – Trichostasis spinulosa

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Updated: 07/28/2016
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Trichodysplasia spinulosa
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Trichodysplasia spinulosa : Rash, Follicular configuration, Sparse eyebrows, Eyelash madarosis, Scaly papules, Scaly plaques
Copyright © 2019 VisualDx®. All rights reserved.