Tufted angioma, previously known as angioblastoma of Nakagawa, is a rare vascular tumor. The name describes the histologic appearance of "tufted" capillary infiltration of the dermis admixed with dilated lymphatic vessels. It is theorized to have a lymphatic origin.

Tufted angioma typically presents at birth (15% of cases) or within the first 5 years of life (50% of cases) as a violaceous plaque or nodule that may be painful. Rarely, it presents later in childhood or in early adulthood. There may be a slight male predominance.

After an initial period of growth, the tumor stabilizes and usually persists; in some patients, it may spontaneously, partially, or completely regress.

Three clinical patterns have been described: tufted angioma without complications, tufted angioma complicated with chronic coagulopathy without thrombocytopenia, and tufted angioma associated with Kasabach-Merritt phenomenon (KMP). KMP is a potentially life-threatening condition characterized by an enlarging vascular lesion, profound thrombocytopenia, consumptive coagulopathy, and often a microangiopathic hemolytic anemia.