Ureteral stricture is distinguished by narrowing of the ureteral lumen resulting in obstruction of urinary flow. Ureteral strictures may be classified as extrinsic or intrinsic, benign or malignant, and iatrogenic or noniatrogenic. Typical clinical symptoms include flank and/or abdominal pain, nausea, vomiting, fever, and infection. However, some patients may be asymptomatic.

Ureteral stricture is most commonly caused by congenital or acquired ureteropelvic junction obstruction or narrowing. Causes include previous treatment of urologic condition, pelvic radiation therapy, urinary diversion surgery, kidney stone passage, renal transplantation, trauma, congenital anomalies, and certain cancers.

Early detection may help prevent severe renal complications. Treatment varies depending on the cause and type of ureteral stricture and should be individualized to the patient. For strictures that develop acutely after trauma, surgery may be suggested. For strictures that develop chronically, endoscopy may be suggested.