Veins of the lower extremities are most often affected. Superficial venous valve incompetence may be due to pre-existing weakness in the vessel wall or valve leaflets or from injury, superficial phlebitis, or venous distension from hormones or hypertension. Deep venous valve dysfunction is generally due to damage from previous deep vein thrombosis.
Common early findings in the legs include pain, pruritus, tingling, nocturnal cramping, and a sensation of "heavy legs." Symptoms are alleviated when legs are elevated. Later stage findings include leg edema, skin changes, and ulceration.
Venous insufficiency is quite common, although the exact prevalence ranges from less than 1%-40% in females and less than 1%-17% in males. Risk factors include older age, familial history, tall height, pregnancy, obesity, immobility, and sedentary lifestyle.
I87.2 – Venous insufficiency (chronic) (peripheral)
20696009 – Peripheral venous insufficiency
- Deep vein thrombosis
- Cellulitis / erysipelas
- Congestive heart failure
- Nephrotic syndrome
- Liver disease
- Endocrine disorders
- Adverse effect of medications including calcium channel blockers, NSAIDs, and oral hypoglycemic agents
- Lymphedema extends into the foot, compared with venous insufficiency which typically spares the foot.