Vestibular papillomatosis is a normal anatomical variant of the vestibular mucosa of the vulva characterized by multiple tiny, soft, smooth, pink papules with a linear configuration and/or symmetric distribution appearing on the mucosa of the vestibule and inner labia minora. The papules are usually asymptomatic, although some patients have reported vulvar pruritus and dyspareunia. The papules usually develop after puberty.

This normal variant is thought to occur in approximately 1% of women, although some studies have found an incidence rate of up to one-third or more.

Papillomatosis of the vulvar vestibule has been reported under a variety of names: vestibular papillae, vulvar squamous papillomatosis, hirsutoid papillomas of the vulvae, and micropapillomatosis.