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Vestibular papillomatosis - Anogenital in
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Vestibular papillomatosis - Anogenital in

Contributors: Mitchell Linder MD, Belinda Tan MD, PhD, David Foster MD, Mary Gail Mercurio MD, Lynne Margesson MD
Other Resources UpToDate PubMed


Vestibular papillomatosis is a normal anatomical variant of the vestibular mucosa of the vulva characterized by multiple tiny, soft, smooth, pink papules with a linear configuration and/or symmetric distribution appearing on the mucosa of the vestibule and inner labia minora. The papules are usually asymptomatic, although some patients have reported vulvar pruritus and dyspareunia. The papules usually develop after puberty.

This normal variant is thought to occur in approximately 1% of women, although some studies have found an incidence rate of up to one-third or more.

Papillomatosis of the vulvar vestibule has been reported under a variety of names: vestibular papillae, vulvar squamous papillomatosis, hirsutoid papillomas of the vulvae, and micropapillomatosis.


D28.0 – Benign neoplasm of vulva

18985003 – Vestibular papillomatosis

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Last Reviewed:10/24/2018
Last Updated:10/24/2018
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Vestibular papillomatosis - Anogenital in
A medical illustration showing key findings of Vestibular papillomatosis : Female genital, Labia minora/vestibule, Linear configuration, Dyspareunia
Clinical image of Vestibular papillomatosis - imageId=313500. Click to open in gallery.  caption: 'A close-up of many tiny papules on the vulval mucosa.'
A close-up of many tiny papules on the vulval mucosa.
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