Vestibular papillomatosis - Anogenital in
This normal variant is thought to occur in approximately 1% of women, although some studies have found an incidence rate of up to one-third or more.
Papillomatosis of the vulvar vestibule has been reported under a variety of names: vestibular papillae, vulvar squamous papillomatosis, hirsutoid papillomas of the vulvae, and micropapillomatosis.
D28.0 – Benign neoplasm of vulva
18985003 – Vestibular papillomatosis
Differential Diagnosis & Pitfalls
- Condyloma acuminatum – Lesions are randomly distributed and not limited to the vestibule; they are firm, and the filiform or cauliflower projections tend to coalesce at the base. Due to having their origin mainly from HPV-related changes, condyloma will have aceto-whitening changes visualized during vulvoscopy.
- Lichen planus – Although frequently part of a generalized disease, lichen planus can be localized to mucosal surfaces including the vaginal mucosa; linear lacy markings (Wickham striae) are common in lichen planus but not in vestibular papillomatosis.
- Molluscum contagiosum
- Fordyce spots – Tiny, yellow papules representing sebaceous glands opening onto the mucosa.