Vestibular papillomatosis - Anogenital in
Alerts and Notices
Synopsis
This normal variant is thought to occur in approximately 1% of women, although some studies have found an incidence rate of up to one-third or more.
Papillomatosis of the vulvar vestibule has been reported under a variety of names: vestibular papillae, vulvar squamous papillomatosis, hirsutoid papillomas of the vulvae, and micropapillomatosis.
Codes
ICD10CM:D28.0 – Benign neoplasm of vulva
SNOMEDCT:
18985003 – Vestibular papillomatosis
Look For
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Condyloma acuminatum – Lesions are randomly distributed and not limited to the vestibule; they are firm, and the filiform or cauliflower projections tend to coalesce at the base. Due to having their origin mainly from HPV-related changes, condyloma will have aceto-whitening changes visualized during vulvoscopy.
- Lichen planus – Although frequently part of a generalized disease, lichen planus can be localized to mucosal surfaces including the vaginal mucosa; linear lacy markings (Wickham's striae) are common in lichen planus but not in vestibular papillomatosis.
- Syringoma
- Molluscum contagiosum
- Fordyce spots – Tiny, yellow papules representing sebaceous glands opening onto the mucosa.
Best Tests
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Management Pearls
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Therapy
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References
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Last Reviewed:10/24/2018
Last Updated:10/24/2018
Last Updated:10/24/2018
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Vestibular papillomatosis - Anogenital in