Vitamin B2 deficiency
Alerts and Notices
Synopsis
Deficiency is more common than appreciated, and vitamin B2 deficiency may coexist with other B vitamin deficiencies due to overall inadequate nutritional status. Vitamin B2 deficiency manifests with mucocutaneous findings. The characteristic oculo-orogenital syndrome is associated with vitamin B2 deficiency, along with vitamin B6 deficiency. Laboratory work may reveal a normocytic anemia.
Individuals with a restricted diet, anorexia nervosa, and those with malabsorption syndromes are at increased risk of developing riboflavin deficiency. Those who avoid dairy products or who have celiac disease, short bowel syndrome, or anorexia nervosa are also more likely to have riboflavin deficiency.
Neonatal deficiency can occur secondary to maternal deficiency during pregnancy or be associated with phototherapy for jaundice.
Codes
ICD10CM:E53.0 – Riboflavin deficiency
SNOMEDCT:
20307000 – Ariboflavinosis
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Differential Diagnosis & Pitfalls
- Thiamine deficiency
- Pellagra
- Folate deficiency
- Vitamin B6 deficiency
- Vitamin B12 deficiency
- Zinc deficiency
- Biotin deficiency
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Last Reviewed:03/06/2018
Last Updated:10/31/2022
Last Updated:10/31/2022