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Vitamin B2 deficiency
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Vitamin B2 deficiency

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Contributors: Abhijeet Waghray MD, Marilyn Augustine MD, Paritosh Prasad MD
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Synopsis

Vitamin B2, also known as riboflavin, is a water-soluble vitamin found in meats, fish, eggs, milk, green vegetables, yeast, and enriched foods. This vitamin is an essential co-enzyme for the metabolism of fat, carbohydrates, and protein. Vitamin B2 also plays a role in steroid metabolism.

Deficiency is more common than appreciated. Symptoms are often nonspecific in vitamin B2 deficiency and frequently overlap with symptoms of other vitamin deficiencies. Pharyngitis, glossitis, stomatitis, anemia, fatigue, and dry and/or cracked lips are common findings. Seborrheic dermatitis may be seen as well. Corneal vascularization may also occur. Laboratory work may reveal a normocytic anemia.

Patients with a restricted diet, anorexia nervosa, and those with malabsorption syndromes are at increased risk of developing riboflavin deficiency. Neonatal deficiency can occur secondary to maternal deficiency during pregnancy or be associated with phototherapy for jaundice.

Treatment includes a combination of increasing dietary intake of vitamin B2 as well as supplementation.

Codes

ICD10CM:
E53.0 – Riboflavin deficiency

SNOMEDCT:
20307000 – Ariboflavinosis

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Last Reviewed: 03/07/2018
Last Updated: 04/19/2018
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Vitamin B2 deficiency
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Vitamin B2 deficiency : Neuropathy peripheral, Pharyngitis, RBC decreased
Clinical image of Vitamin B2 deficiency
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