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Vitamin E deficiency
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Vitamin E deficiency

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Contributors: Abhijeet Waghray MD, Paritosh Prasad MD, Eric Ingerowski MD, FAAP
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Synopsis

Vitamin E deficiency : Areflexia, Ataxia, Position sense decreased, Vibratory sense decreased, Hemolytic anemia, Muscle weakness, Neuropathy peripheral, Reflexes decreased
Vitamin E deficiency is a rare cause of ataxia, neuropathy, and retinopathy. Vitamin E is present in many oils, meats, eggs, leafy vegetables, and grains, so poor nutrition is not typically a cause of deficiency in developed countries. Since vitamin E is a fat-soluble vitamin, diseases that impair absorption of fat-soluble vitamins (eg, cystic fibrosis or pancreatic insufficiency, extensive small bowel resection) may cause deficiency. Abetalipoproteinemia can also cause a secondary vitamin E deficiency.

Onset of symptoms is typically gradual, with ataxia accompanied by impairment of dorsal column (vibratory / position) sensation and hyporeflexia.

Vitamin E deficiency is managed with treatment of the underlying cause and oral supplementation.

Codes

ICD10CM:
E56.0 – Deficiency of vitamin E

SNOMEDCT:
54137008 – Vitamin E deficiency

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Differential Diagnosis & Pitfalls

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Last Reviewed:02/08/2018
Last Updated:01/25/2022
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Vitamin E deficiency
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A medical illustration showing key findings of Vitamin E deficiency : Areflexia, Ataxia, Position sense decreased, Vibratory sense decreased, Hemolytic anemia, Muscle weakness, Neuropathy peripheral, Reflexes decreased
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