Prognosis is poor for children at the most severe end of the spectrum, who usually die within a year (patients who develop liver disease or leukodystrophy). Milder cases may experience slower progression and have a longer life expectancy, but it is not often predictable.
Zellweger spectrum disorders lack a curative therapy; however, supportive therapeutic options are available.
E71.510 – Zellweger syndrome
88469006 – Zellweger syndrome