Acquired pancytopenia in Adult
Acquired pancytopenia can be caused by bone marrow replacement from leukemia, metastatic carcinoma, myelodysplastic syndrome, or myeloproliferative diseases. Bone marrow failure, such as in aplastic anemia, may also lead to acquired pancytopenia. Severe malnutrition or malabsorption can rarely lead to pancytopenia.
Treatment depends on the underlying cause. Red blood cell and platelet transfusions can provide symptomatic treatment.
D61.818 – Other pancytopenia
5876000 – Acquired pancytopenia
- Acute leukemia (eg, acute lymphoid leukemia, acute promyelocytic leukemia, acute myelogenous leukemia)
- Lymphoma infiltrating the bone marrow
- Myelodysplastic syndrome
- Human immunodeficiency disease or viral disease
- Infiltrative disease metastatic to the bone marrow such as solid tumors (ie, breast cancer, prostate cancer)
- Drug-induced pancytopenia (see Drug Reaction list)
- Chemotherapy effects
- Aplastic anemia
- Heritable causes such as Fanconi anemia