Acrokeratosis paraneoplastica
See also in: Nail and Distal DigitAlerts and Notices
Synopsis
Three stages of disease were originally delineated by Bazex and Griffiths:
- Stage I – Erythema and psoriasiform scaling of fingers, toes, and ear helices, and violaceous erythema with pityriasiform scaling of the nose. Nail changes include subungual hyperkeratosis, onychodystrophy, and onycholysis. Nail folds are involved and may be tender.
- Stage II – Palms and soles involved with keratoderma. Facial lesions involve upper lip and pinna. Symptoms and signs of malignancy usually present.
- Stage III – Legs, knees, thighs, arms, trunk, and scalp may be involved.
Codes
ICD10CM:L85.1 – Acquired keratosis [keratoderma] palmaris et plantaris
SNOMEDCT:
238640007 – Acrokeratosis paraneoplastica of Bazex
Look For
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Psoriasis
- Onychomycosis
- Reactive arthritis (Reiter syndrome)
- Pityriasis rubra pilaris
- Palmoplantar keratoderma
- Lupus erythematosus / lichen planus overlap
- Pityriasis rosea
- Eczema
- Systemic contact dermatitis
- Immunobullous disease
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Therapy
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References
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Last Reviewed:10/08/2018
Last Updated:05/22/2019
Last Updated:05/22/2019
Acrokeratosis paraneoplastica
See also in: Nail and Distal Digit