Contents

SynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferences

View all Images (24)

Bullosis diabeticorum
Other Resources UpToDate PubMed

Bullosis diabeticorum

Contributors: Serena Dienes BSc, John Zampella MD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Bullosis diabeticorum (BD), also known as bullous eruption of diabetes mellitus or diabetic bullae, occurs in about 0.5% of people with diabetes (type 1, type 2) and has an unknown pathogenesis. The co-occurrence of neuropathy and nephropathy suggests an underlying microangiopathy. Bullae seen in BD are noninflammatory and often develop rapidly. Most people will be asymptomatic or experience mild burning and discomfort. However, those with large bullae on the feet (particularly in older adults) may become unable to wear shoes, leading to a significant reduction in mobility and autonomy.

BD often develops in long-standing, uncontrolled diabetes, although there are reports of BD as the presenting sign of diabetes. Disabling BD has also been reported in older adult patients with optimal glycemic control. Bullae often resolve on their own without scarring, but recurrence is common, and new bullae can continue to form over a period of years. The average age of onset is 55 years, and there is a 2:1 male-to-female ratio.

Codes

ICD10CM:
E13.628 – Other specified diabetes mellitus with other skin complications

SNOMEDCT:
48951005 – Bullosis diabeticorum

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Subscription Required

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Reviewed:12/16/2023
Last Updated:12/17/2023
Copyright © 2024 VisualDx®. All rights reserved.
Bullosis diabeticorum
A medical illustration showing key findings of Bullosis diabeticorum : Forearm, Lower leg, Feet or toes
Clinical image of Bullosis diabeticorum - imageId=108152. Click to open in gallery.  caption: 'A tense hemorrhagic bulla on the sole, abutting the plantar aspect of the toes.'
A tense hemorrhagic bulla on the sole, abutting the plantar aspect of the toes.
Copyright © 2024 VisualDx®. All rights reserved.