ContentsSynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyDrug Reaction DataReferencesInformation for PatientsView all Images (13)
Cheilitis - Oral Mucosal Lesion
See also in: Overview
Print
Other Resources UpToDate PubMed

Cheilitis - Oral Mucosal Lesion

See also in: Overview
Print Patient Handout Images (13)
Contributors: Carl Allen DDS, MSD, Sook-Bin Woo MS, DMD, MMSc
Other Resources UpToDate PubMed

Synopsis

Lips of patients with cheilitis appear dry and scaly and may have one or more fissures. Often the lips are painful, and there may or may not be associated edema and erythema.

Cheilitis is one of the more challenging oral problems to diagnose and treat. Many cases represent a factitial disorder related to lip-licking habits, and it can be difficult to convince patients that the vermilion zone of the lip should be dry (the "wet line" is the demarcation between the labial mucosa and vermilion zone).

Some cases of cheilitis are related to contact hypersensitivity reactions to compounds found in products that commonly come into contact with the vermilion zone of the lip, including cosmetics, lip balms, toothpastes, and sunscreens (oxybenzone [benzophenone-3]).

Other cases of cheilitis are due to candidal infection related to chronic lip-licking or to the use of petrolatum-based materials that are applied to the lips. The petrolatum seals in moisture, allowing the candidal organism to thrive in the moist keratin that results.

Retinoids (isotretinoin and acitretin) are also frequent causes for this problem. High doses of vitamin A, lithium, chemotherapeutic agents (busulfan and actinomycin), d-penicillamine, isoniazid, and phenothiazine have also been reported to cause cheilitis.

Codes

ICD10CM:
K13.0 – Diseases of lips

SNOMEDCT:
7847004 – Cheilitis

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

Subscription Required

References

Subscription Required

Last Updated: 09/27/2017
Copyright © 2019 VisualDx®. All rights reserved.
Cheilitis - Oral Mucosal Lesion
See also in: Overview
Print 13 Images
View all Images (13)
(with subscription)
Cheilitis : Erythema, Lip scaling, Lips
Clinical image of Cheilitis
Copyright © 2019 VisualDx®. All rights reserved.