Potentially life-threatening emergency
Disseminated candidiasis in Child
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Synopsis

Organ systems commonly affected include the kidneys, with over half of patients manifesting some form of renal involvement, which may include candiduria, hypertension, renal failure, abscess formation, and the development of fungal balls leading to obstruction and hydronephrosis. Central nervous system (CNS) involvement is also frequent, occurring in one-third of cases, and may result in abscess formation. Endophthalmitis is seen in almost half of all cases.
Cutaneous manifestations of systemic Candida infection include a generalized dermatitis, which may be followed by desquamation. Other common skin findings range from discrete pustules and erythematous or pink papules to nodules and necrotic skin. Macules may also be present. Chorioretinitis is characteristic.
Generalized symptoms include spiking fevers, chills, headache, hypotension, respiratory distress, blurred vision, and prostration. Myalgias, arthralgias, and osteoarthritis may be present. Pneumonia occurs in 70% of patients.
Systemic candidiasis is a serious illness that is associated with significant morbidity and mortality.
Candida auris
Candida auris is an emerging cause of candidemia that is notable for high rates of mortality and for drug resistance. See below and the US Centers for Disease Control and Prevention (CDC) Information for Laboratorians and Health Professionals for more detailed information.
Codes
ICD10CM:B37.7 – Candidal sepsis
SNOMEDCT:
70572005 – Disseminated candidiasis
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Drug Reaction Data
Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.Subscription Required
References
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Last Reviewed:03/22/2023
Last Updated:03/23/2023
Last Updated:03/23/2023