Drug-induced dyspepsia
Alerts and Notices
Important News & Links
Synopsis
The most common drugs that cause dyspepsia include aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs), which can contribute to mucosal damage, ulceration, and bleeding complications. Other associated medications include iron, antibiotics, antihypertensives, narcotics, estrogens, theophylline, selective serotonin reuptake inhibitors (SSRIs), niacin, digoxin, corticosteroids, levodopa, and hypoglycemic agents. These medications can cause symptoms by causing direct gastric mucosal injury (eg, NSAIDs), a change in gastrointestinal sensorimotor function, worsening GERD, or idiopathic mechanisms.
Management of drug-induced dyspepsia includes drug discontinuation, assessment of underlying pathology, and symptom control.
Codes
T50.995A – Adverse effect of other drugs, medicaments and biological substances, initial encounter
SNOMEDCT:
299969005 – Drug-induced dyspepsia
Look For
Subscription Required
Diagnostic Pearls
Subscription Required
Differential Diagnosis & Pitfalls
Subscription Required
Best Tests
Subscription Required
Management Pearls
Subscription Required
Therapy
Subscription Required
Drug Reaction Data
Subscription Required
References
Subscription Required
Last Updated:01/14/2019