Erythema gyratum repens
EGR is associated with internal malignancy in 70% of patients. EGR is most commonly associated with lung cancer, followed by esophageal cancer and breast cancer. EGR has also been noted in association with several nonmalignant conditions such as tuberculosis, autoimmune bullous diseases, CREST syndrome, psoriasis, pityriasis rubra pilaris, ichthyosis, and hypereosinophilic syndrome. The male-to-female ratio is 2:1, and the average age of onset is in the seventh decade.
L53.8 – Other specified erythematous conditions
77300003 – Erythema gyratum repens
Differential Diagnosis & Pitfalls
- Erythema annulare centrifugum (EAC) – EGR advances at a much faster rate than EAC.
- Erythema migrans (marker of Lyme disease)
- Annular urticaria
- Urticarial phase of bullous pemphigoid
- Erythema multiforme
- Tinea corporis
- Erythema marginatum (rheumatic fever)
- Necrolytic migratory erythema (associated with glucagonomas)
- If the rash is psoriasiform, check for other stigmata of psoriasis.
- Subacute cutaneous lupus erythematosus
- Granuloma annulare
- Secondary syphilis
- Tinea imbricata