ContentsSynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyDrug Reaction DataReferences
Esophageal stricture
Other Resources UpToDate PubMed

Esophageal stricture

Contributors: Michael W. Winter MD, Christine Osborne MD, Desiree Rivera-Nieves MD, Khaled Bittar MD, Nishant H. Patel MD
Other Resources UpToDate PubMed

Synopsis

Esophageal stricture is a broad term referring to a narrowing of the esophageal lumen. The stricture can be caused by a number of different etiologies: inflammation (long-standing esophagitis), radiation therapy, benign or malignant mass lesions (internal or external compression), caustic ingestions, and others.

Caustic substances include ammonium hydroxide, sodium and potassium hydroxide (lye), sodium hypochlorite (bleach), acetic acid, hydrochloric acid, oxalic acid, phosphoric acid, selenious acid, sulfuric acid, nitric acid, cationic detergents, hydrofluoric acid, hydrogen peroxide, phenol, and zinc chloride. Frequently, ingestion of these substances by adults and adolescents may be deliberate. Caustic-induced injuries in children in developed countries have increased due to ingestion of the liquid inside laundry- and dish-detergent capsules ("pods").

Esophageal strictures most commonly present as dysphagia, more typically to solids but sometimes to liquids, which can progressively worsen. Additional symptoms include heartburn, odynophagia, acute or chronic food impactions, chest pain (referred), and weight loss if oral intake is compromised.

The etiology of esophageal strictures can be organized into benign causes (peptic strictures [the most common], esophageal rings, esophageal webs, radiation-related injury, strictures at anastomoses, or secondary to caustic injury) or malignant causes (esophageal cancer being the most common). It is uncommon for esophageal strictures to be asymptomatic, but, depending on the underlying etiology, they can be rapidly progressive or have an insidious onset.

Codes

ICD10CM:
K22.2 – Esophageal obstruction

SNOMEDCT:
63305008 –  Stricture of esophagus

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

Subscription Required

References

Subscription Required

Last Reviewed:09/03/2020
Last Updated:09/14/2020
Copyright © 2021 VisualDx®. All rights reserved.
Esophageal stricture
Print  
Esophageal stricture : Vomiting, Dysphagia, Dyspepsia
Copyright © 2021 VisualDx®. All rights reserved.