Familial hypocalciuric hypercalcemia
Classic presentation includes:
E83.52 – Hypercalcemia
237885008 – Familial Hypocalciuric Hypercalcemia
- Primary hyperparathyroidism – urine calcium will be elevated
- Hyperparathyroidism secondary to renal disease – serum calcium should be normal or low, serum phosphorous should be elevated or normal, renal function should be abnormal
- Hyperparathyroidism secondary to hypocalcemia – as in vitamin D deficiency or intestinal disorders that impair calcium absorption. Calcium would be normal or low, and 25-OH vitamin D will likely be low.
- Lithium use (see lithium nephropathy) – in this case, familial hypocalciuric hypercalcemia can be closely mimicked, with lowered urine calcium excretion and potentially elevated serum calcium. This will likely resolve with the withdrawal of lithium, but may not if lithium use is chronic.