Glomus tumor - Nail and Distal Digit
There is a familial variant of glomus tumor, linked to chromosome 1p21–22, encoding the glomulin gene (GLMN). Multiple glomus tumors are inherited as an autosomal dominant trait and are usually found on the legs. They are often present in younger children. Neurofibromatosis type 1 may present with numerous glomus tumors involving the digits. They are often painless.
For more information on inherited multiple glomus tumors, see OMIM.
D18.00 – Hemangioma unspecified site
403969002 – Glomus tumor
- Eccrine spiradenoma
- Subungual hematoma
- Squamous cell carcinoma
- Lobular capillary hemangioma (pyogenic granuloma)
- Acute paronychia
- Osteoid osteoma
- Foreign body
- Painful onycholysis may occur secondary to a subungual vesicle or bulla, as may be seen in porphyria, pseudoporphyria, or other autoimmune blistering diseases.
- Benign: onychopapilloma, wart, warty dyskeratoma, or single lesion of lichen planus
- Malignant: Bowen disease, squamous cell cancer, melanoma in situ, and basal cell carcinoma