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Glomus tumor - Nail and Distal Digit
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Glomus tumor - Nail and Distal Digit

See also in: Overview
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Contributors: Shari Lipner MD, PhD, Belinda Tan MD, PhD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

A glomus tumor is benign neoplasm that originates from cells of the glomus body. Glomus bodies are highly concentrated in the fingertips, so not surprisingly, glomus tumors are most common in the hands and subungual region. Small single tumors are most frequent, and women are affected more often than men. Most patients are between 30 and 50 years of age. Subungual glomus tumors may present with a triad: pain, pinpoint tenderness, and cold sensitivity. Physical examination may show a small reddish or bluish papule several millimeters in diameter. Some may present as a longitudinal erythronychia with distal notching or overlying longitudinal fissure.

There is a familial variant of glomus tumor, linked to chromosome 1p21–22, encoding the glomulin gene (GLMN). Multiple glomus tumors are inherited as an autosomal dominant trait and are usually found on the legs. They are often present in younger children. Neurofibromatosis type 1 may present with numerous glomus tumors involving the digits. They are often painless.

For more information on inherited multiple glomus tumors, see OMIM.

Codes

ICD10CM:
D18.00 – Hemangioma unspecified site

SNOMEDCT:
403969002 – Glomus tumor

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Other causes of painful nail:
Differential diagnosis of longitudinal erythronychia – single band:
Differential diagnosis of longitudinal erythronychia – multiple bands, usually multiple nails:

Best Tests

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Management Pearls

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Therapy

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References

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Last Reviewed: 02/08/2017
Last Updated: 10/27/2017
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Glomus tumor - Nail and Distal Digit
See also in: Overview
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Glomus tumor : Painful skin lesions, Subungual papule or tumor, Tender skin lesion
Clinical image of Glomus tumor
A close-up of a deep blue-purple papule with a lighter border.
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