Potentially life-threatening emergency
Heat stroke
Alerts and Notices
Synopsis
Meningitis, neuroleptic malignant syndrome, toxic ingestion, and other conditions may mimic heat stroke, so the diagnosis must carefully consider clinical history. Treatment primarily consists of physical cooling (evaporative, ice water, etc), fluid resuscitation, and monitoring for complications.
Codes
ICD10CM:T67.01XA – Heatstroke and sunstroke, initial encounter
SNOMEDCT:
52072009 – Heat Stroke
Look For
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Meningitis (eg, aseptic, bacterial, fungal) / encephalitis
- Neuroleptic malignant syndrome
- Serotonin syndrome
- Alcohol withdrawal
- Other drug-induced causes of hyperthermia (lamotrigine, progesterone, hallucinogenics, stimulants, monoamine oxidase inhibitors) or altered mental status (NSAIDs, opiates, antidepressants, antihistamines, anticholinergics)
- Hyperthyroidism
- Sepsis
- Tetanus
Best Tests
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Management Pearls
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Therapy
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Drug Reaction Data
Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.Subscription Required
References
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Last Reviewed:05/08/2019
Last Updated:05/13/2019
Last Updated:05/13/2019