Hungry bone syndrome

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Contributors: Catherine Moore MD

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Synopsis

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An uncommon metabolic syndrome characterized by prolonged and significant hypocalcemia, hypophosphatemia, and hypomagnesemia following surgical parathyroidectomy for severe primary or tertiary hyperparathyroidism. The condition results from the sudden decrease in parathyroid hormone release, resulting in increased mineral uptake by bones. Signs and symptoms also include proximal muscle weakness, fatigue, and vitamin D deficiency.

Management involves replacing calcium loss with high doses of calcium with vitamin D. Preventive management is under study. Magnesium and phosphate levels should also by monitored.

Codes

ICD10CM:
E83.81 – Hungry bone syndrome

SNOMEDCT:
237883001 – Hungry bones syndrome

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