Jacquet erosive diaper dermatitis - Anogenital in
The clinical presentation includes papules or nodules with overlying superficial erosions as well as erosions or ulcers with elevated borders in the genital or perirectal region. Some reports of pseudoverrucous lesions can be found. Patients often experience pruritus and burning.
Treatment can be difficult; the most effective treatment reported is normalization of the local integumental environment and of bowel / bladder habits.
L22 – Diaper dermatitis
91487003 – Jacquet's dermatitis
- Infectious (bacterial / fungal / herpes simplex virus) – It is important to rule these out as potential agents as they can appear clinically similar. Polymerase chain reaction (PCR) and culture will be negative in Jacquet.
- Langerhans cell histiocytosis – Petechiae and nonhealing erosions in the diaper area often require histology for definitive diagnosis. Biopsy will show proliferation of histiocytes.
- Acrodermatitis enteropathica – Rash commonly described as resembling "peeling paint." Found in the perineal region of infants around 6 months of age. It is caused by zinc deficiency. Look for similar lesions around the mouth, a recent history of weaning, and low serum alkaline phosphatase to make this diagnosis.
- Granuloma gluteale infantum – Purple nodules in the diaper region of varying size; also thought to be caused by diaper irritation.
- Pseudoverrucous papules and nodules – This may represent a spectrum of the same disease, but lesions appear more verrucous. Treatment is similar to that for Jacquet.
- Bullous pemphigoid