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Lung cancer
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Lung cancer

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Contributors: Abhijeet Waghray MD, Paritosh Prasad MD
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Synopsis

Lung cancer is the leading cause of cancer-related deaths in both men and women worldwide, although mortality rates have started to decline, likely reflecting a decrease in smoking. The decline has been greatest in men, and in fact, the incidence of lung cancer in the United States is now higher in young women of Northern European and Hispanic descent than in young men (reasons are as yet unknown; they have not been found to be associated with sex differences in smoking behavior).

Greater than 95% of lung cancers can be categorized as either small cell lung cancer (SCLC) or non-small cell lung cancer (NSCLC), with adenocarcinoma and squamous cell carcinoma being the most common NSCLC. Carcinoid tumors and mesothelioma may also arise in the lung but are less common. The lungs are also a common site of metastatic cancer.

Environmental and lifestyle factors have been associated with the development of lung cancer. These include cigarette smoking, environmental toxins, and radiation therapy. Lung cancer screening may be advisable in select patients.

The prognosis and treatment of lung cancer is dependent on the type of cancer present, lymph node involvement, and the presence or absence of metastasis. Treatment options include surgical resection, chemotherapy, and/or radiation.

Codes

ICD10CM:
C34.90 – Malignant neoplasm of unspecified part of unspecified bronchus or lung

SNOMEDCT:
363358000  – Malignant tumor of lung

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Reviewed: 06/14/2018
Last Updated: 11/15/2018
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Lung cancer
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Lung cancer : Chest pain, Cough, Fatigue, Hoarseness, Nail clubbing, Weight loss, Anorexia, Dyspnea, Hemoptysis
Imaging Studies image of Lung cancer
There is a large mass within the right lung in a perihilar location compatible with bronchogenic carcinoma. There is metastatic disease involving the right 5th rib with bony destruction, and a large extrapleural mass.
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