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Metastatic cutaneous carcinoma - Hair and Scalp
See also in: Overview
Other Resources UpToDate PubMed

Metastatic cutaneous carcinoma - Hair and Scalp

See also in: Overview
Contributors: Jeffrey M. Cohen MD, Belinda Tan MD, PhD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Approximately 1%-4.5% of internal cancers metastasize to the skin. The most frequent primary tumors are carcinomas of the breast, stomach, lung, uterus, kidney, ovary, colon, or bladder. The lesions may represent direct extension to the skin or local or distant metastasis via lymphatic or hematogenous dissemination of tumor cells.

Cutaneous metastases usually indicate a very poor prognosis, with an approximate 75% one-year mortality rate. Patients may be any age but are typically older adults. The interval between detection of the primary tumor and development of cutaneous metastases may be on the order of years, or skin metastases may be the first manifestation of an internal malignancy.

In addition to the skin lesion(s), patients with previously undiagnosed cancer may also notice a palpable mass, pallor, or weight loss. A personal history of previous carcinoma should raise the index of suspicion for a cutaneous metastasis.

Related topic: Subungual metastases

Codes

ICD10CM:
C79.2 – Secondary malignant neoplasm of skin

SNOMEDCT:
94579000 – Secondary malignant neoplasm of skin

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Differential Diagnosis & Pitfalls

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Therapy

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Last Reviewed:10/18/2019
Last Updated:12/06/2019
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Metastatic cutaneous carcinoma - Hair and Scalp
See also in: Overview
Metastatic cutaneous carcinoma : Abdomen, Chest, Neck, Umbilicus, Erythematous patches
Clinical image of Metastatic cutaneous carcinoma
A cluster of shiny reddish papules and nodules on the central chest.
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