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Metastatic tumors to the orbit - External and Internal Eye
Other Resources UpToDate PubMed

Metastatic tumors to the orbit - External and Internal Eye

Contributors: Aditi Jani MD, Jeffrey M. Cohen MD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Metastatic tumors to the orbit occur in both children and adults and can be the presenting sign of systemic malignancy. The most common presenting signs and symptoms are eyelid edema, red eye, diplopia, vision loss, pain, strabismus, and proptosis. The presentation of orbital metastases generally depends on the position of the tumor and which structures, such as cranial nerves, the tumor compresses.

In children, neuroblastoma and leukemia are the most common primary tumors. In adults, breast, lung, and prostate carcinoma are the most frequently seen primary tumors, but any primary tumor can metastasize to the orbit. Vision and pupils should be checked in any orbital process. Metastatic tumors have been known to cause ptosis, myosis, and anhidrosis (Horner syndrome), so close examination of the pupil is necessary.

Orbital metastases are generally associated with a poor prognosis, and one study found an average survival of 1.5 years after diagnosis, independent of primary tumor type.

Related topic: Metastatic tumors to the choroid

Codes

ICD10CM:
C79.49 – Secondary malignant neoplasm of other parts of nervous system

SNOMEDCT:
363462005 – Malignant tumor of orbit

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Last Reviewed:10/31/2019
Last Updated:02/07/2020
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Metastatic tumors to the orbit - External and Internal Eye
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Metastatic tumors to the orbit : Eye pain, Diplopia, Eyelid edema, Limited ocular motility, Proptosis, Red eye
Copyright © 2021 VisualDx®. All rights reserved.