Mucous membrane pemphigoid - Anogenital in
MMP is almost twice as common in females as it is in males, and it is seen most frequently in older individuals. MMP affects the mucous membranes and, less commonly, the skin. The mouth is involved most frequently (painful erosions and ulcers), followed by the conjunctiva (corneal injection, scarring that leads to symblepharon and blindness).
Nasal, laryngeal, and esophageal mucosal surfaces can also be affected, leading to epistaxis, hoarseness, or dysphagia, respectively. Anogenital involvement in women may present with vulvovaginal or perianal blisters, erosions, and scarring.
Cutaneous disease, when present, most frequently accompanies mucous membrane disease. Occasionally, cutaneous blistering and scarring dominate the clinical picture (so-called Brunsting-Perry variant).
L12.1 – Cicatricial pemphigoid
34250006 – Cicatricial pemphigoid
- Bullous pemphigoid, most frequently seen in the elderly, presents with nonfragile blisters that cause less scarring because they occur closer to the skin surface.
- Pemphigus vulgaris presents with flaccid, fragile blisters.
- The lesions of erythema multiforme are round, light-red spots with concentric zones and, at times, blisters and exudates.
- Lichen sclerosus lacks the vesicles and erosions seen in MMP.
- Genital erosive lichen planus
- Genital aphthous ulcers
- Behçet disease
- Reactive nonsexually related acute genital ulceration (RNSRAGU)
- Hailey-Hailey disease occurs primarily in body folds such as the inguinal fold.
Last Updated: 01/23/2018