Non-Hodgkin lymphoma
See also in: Oral Mucosal LesionAlerts and Notices
Synopsis
NHLs are subclassified based on the different types of lymphocytes involved. They can include B-lymphocytes, T-lymphocytes, and natural killer cells. B-cell lymphomas are the most common and include diffuse B-cell lymphoma, cutaneous B-cell lymphoma, follicular lymphoma, chronic lymphocytic leukemia, acute lymphocytic leukemia, mantle cell lymphoma, marginal zone lymphomas, Burkitt lymphoma, lymphoplasmacytic lymphoma, and central nervous system lymphoma. T-cell lymphomas include peripheral T-cell lymphoma, anaplastic large cell lymphoma, angioimmunoblastic T-cell lymphoma, and adult T-cell lymphoma / leukemia.
The signs and symptoms of NHL are very heterogeneous, depending on the subtype of malignancy. It can involve lymph nodes, skin, the gastrointestinal system, the liver, the spleen, bone marrow, or any other part of the body.
It is critical to diagnose the type of NHL in order to correctly treat it.
Codes
ICD10CM:C85.90 – Non-Hodgkin lymphoma, unspecified, unspecified site
SNOMEDCT:
118601006 – Non-Hodgkin's lymphoma
Look For
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Reactive lymphadenopathy (infectious, autoimmune, drug-induced)
- Hodgkin lymphoma
- Other malignancy
Best Tests
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Management Pearls
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Therapy
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Drug Reaction Data
Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.Subscription Required
References
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Last Reviewed:03/18/2021
Last Updated:03/31/2021
Last Updated:03/31/2021
Non-Hodgkin lymphoma
See also in: Oral Mucosal Lesion