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Solitary neurofibroma in Adult
Other Resources UpToDate PubMed

Solitary neurofibroma in Adult

Contributors: Noah Craft MD, PhD, Lindy P. Fox MD, Belinda Tan MD, PhD, Lowell A. Goldsmith MD, MPH
Other Resources UpToDate PubMed


Solitary neurofibromas are are well-circumscribed, non-encapsulated, benign tumors of neuromesenchymal tissue (Schwann cells, perineural cells, fibroblasts, and mast cells) with nerve axons. They present as asymptomatic, skin-colored or violaceous, rubbery papules or nodules. They can occur anywhere on the body. Solitary neurofibromas occur primarily in adulthood and late adolescence and are not an indication of neurofibromatosis. There is no sex predilection.


D21.9 – Benign neoplasm of connective and other soft tissue, unspecified

404030000 – Solitary neurofibroma

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Last Updated:11/01/2018
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Solitary neurofibroma in Adult
A medical illustration showing key findings of Solitary neurofibroma : Smooth nodule, Smooth papule, Trunk
Clinical image of Solitary neurofibroma - imageId=84289. Click to open in gallery.  caption: 'A close-up of a smooth pinkish nodule.'
A close-up of a smooth pinkish nodule.
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