Treatment includes hemodialysis, although there may be a 1- to 2-day lag time before significant improvements in mental status are appreciated.
If a patient fails to improve with hemodialysis, alternate causes of acute encephalopathy should be sought.
N25.9 – Disorder resulting from impaired renal tubular function, unspecified
35145002 – Uremic encephalopathy
Differential Diagnosis & Pitfalls
- Nonconvulsive status epilepticus
- Anti-N-methyl-D-aspartate (anti-NMDA) receptor antibody syndrome
- Anticholinergic toxicity
- Creutzfeldt-Jakob disease
- Human immunodeficiency virus encephalopathy
- Progressive multifocal leukoencephalopathy
- Herpes simplex virus encephalitis
- Hepatic encephalopathy
- Hashimoto encephalopathy
- Drug intoxication (many)