Rare disorder in which secondary male sex characteristics develop in a female, caused by adrenal androgen secretion, cortisol excess, or a number of medications. Associated with polycystic ovarian syndrome, adrenal carcinoma, and congenital adrenal hyperplasia. Characterized by amenorrhea, voice deepening, hirsutism, infertility, and clitoromegaly. In pregnancy, a woman with gestational hyperandrogenism may develop hirsutism and virilism; her female fetus may develop irreversible virilization.
Treatments may include antiandrogens and cosmetic procedures.
Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.