Seventy percent of peptic ulcers are asymptomatic, and 60% of peptic ulcers heal spontaneously.
Gastric ulcers usually occur due to Helicobacter pylori infection or ingestion of nonsteroidal anti-inflammatory drugs (NSAIDs). Other risk factors include smoking, excessive alcohol consumption, steroids, and high-salt diet. Less common etiologies include ischemia in the setting of severe burns (Curling ulcer) and uncontrolled activation of parietal cells due to vagal stimulation via elevated intracranial pressure (Cushing ulcer).
Gastric ulcers may lead to hemorrhage, perforation, infection, or scar tissue if left untreated.
K25.9 – Gastric ulcer, unspecified as acute or chronic, without hemorrhage or perforation
397825006 – Gastric ulcer
- Gastroesophageal reflux disease
- Functional indigestion / dyspepsia or drug-induced dyspepsia
- Esophagitis, drug-induced esophagitis, esophageal ulcer
- Duodenitis, duodenal ulcer
- Variceal bleed / chronic liver disease
- Inflammatory bowel disease (eg, Crohn disease, ulcerative colitis), diverticulitis, colon cancer
- Gastric cancer
- Dieulafoy ulcer, arteriovenous malformation
- Mallory Weiss tear
- Melena mimics (caused by iron supplements and medications containing bismuth, eg, Pepto-Bismol)
- Biliary colic, cholecystitis, cholelithiasis
- Pancreatitis (acute and chronic)
- Superior mesenteric artery syndrome
- Acute mesenteric ischemia
- Myocardial infarction
- Angina (stable, unstable)
- Behçet disease (vasculitis)
Last Updated: 06/06/2017