An ocular drug reaction may include, but is not limited to, the following signs: conjunctival injection (red eye), epiphora (excessive tearing), mydriasis (dilated pupils), miosis (constricted pupils), anisocoria (unequal pupil size), nystagmus (rapid, involuntary eye movements), strabismus (misalignment of eyes), retinopathy (damage to the retina), eyelid ptosis (drooping eyelid), discharge, change in ocular pressure, hemorrhage, and edema. Symptoms may include vision loss, blindness, night blindness, blurry vision, diplopia (double vision), amblyopia (decreased vision in one eye), myopia (nearsightedness), photophobia (increased reaction to light), photopsia (flashing lights), xerophthalmia (dry eyes), vitreous floaters, burning, irritation, and pain. Uncommonly, visual disturbances may include palinopsia (images persist after the actual object is no longer in sight), metamorphopsia (distorted sight that may result in straight objects appearing wavy), and scotoma (visual field defect localized within the normal visual field).
Related diagnoses with possible drug etiology:
- Anterior nongranulomatous uveitis
- Anterior ischemic optic neuropathy
- Argyria
- Blepharitis
- Blepharoptosis
- Cataracts
- Central retinal artery occlusion
- Central retinal vein occlusion
- Conjunctivitis (allergic, follicular)
- Drug-induced corneal deposits
- Ectropion
- Esotropia
- Episcleritis (diffuse and nodular)
- Exotropia
- Glaucoma (acute angle closure and neovascular)
- Hyphema
- Iritis
- Keratitis (interstitial and marginal)
- Lens subluxation or dislocation
- Macular hole
- Ocular cicatricial pemphigoid
- Optic neuritis
- Papilledema
- Proptosis
- Retinal detachment
- Retinal tear
- Scleritis (diffuse, nodular, necrotizing)
- Subconjunctival hemorrhage
- Toxic conjunctivitis
- Uveitis