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Parathyroid adenoma
Other Resources UpToDate PubMed

Parathyroid adenoma

Contributors: Benjamin L. Mazer MD, MBA, Marilyn Augustine MD
Other Resources UpToDate PubMed


Benign condition characterized by a proliferation of parathyroid cells, often in a nodule within the parathyroid gland. Parathyroid adenomas are often responsible for hyperparathyroidism, which leads to abnormal production of parathyroid hormone, resulting in hypercalcemia. When symptomatic, patients may present with constipation, nausea, muscle weakness, lethargy, memory impairment, and depressed mood.


D35.1 – Benign neoplasm of parathyroid gland

128474007 – Parathyroid adenoma

Differential Diagnosis & Pitfalls

Parathyroid masses:
  • Parathyroid hyperplasia
  • Parathyroid lipoadenoma
  • Parathyroid carcinoma
  • Ectopic thyroid tissue
  • Thyroid cancer
  • Multinodular goiter
  • Thyroiditis
  • Metastasis to thyroid
  • Multiple endocrine neoplasia (Multiple endocrine neoplasia type 1, Multiple endocrine neoplasia type 2A)
  • Secondary hyperparathyroidism
  • Tertiary hyperparathyroidism
  • Chronic kidney disease
  • Hypercalcemia of malignancy
  • Familial hypocalciuric hypercalcemia
  • Multiple myeloma
  • Hypervitaminosis D
  • Sarcoidosis

Best Tests

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Last Updated:08/11/2016
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Parathyroid adenoma
A medical illustration showing key findings of Parathyroid adenoma : Fatigue, Muscle weakness, Asthenia, Ca elevated
Copyright © 2024 VisualDx®. All rights reserved.