Psoriasis - Nail and Distal Digit
See also in: Overview,Anogenital,Hair and ScalpAlerts and Notices
Important News & Links
Synopsis

Psoriasis is a disorder of skin hyperproliferation that commonly involves the nail unit. Approximately 80%-90% of patients with psoriasis display nail manifestations at some point in their lifetime. The manifestations of psoriasis may be limited exclusively to the nails in up to 10% of patients. Nail psoriasis has a significant effect on quality of life and is associated with higher risk of severe skin disease. Furthermore, nail involvement with psoriasis is a risk factor for developing psoriatic arthritis.
The most common nail findings in psoriasis are pitting, nail plate yellowing, onycholysis, subungual hyperkeratosis, splinter hemorrhages, and "oil spots." Psoriasis may also involve the nail folds in the form of swelling and chronic paronychia. Toenail findings are less frequent than psoriatic changes in the fingernails. When they do occur, subungual hyperkeratosis and yellow discoloration of the nail plate are the predominant findings.
Pediatric Patient Considerations:
Nail psoriasis in children is associated with more severe disease in most studies. It may be more common in boys than girls. The prevalence of nail psoriasis in children is 15%-19%. Furthermore, psoriasis is believed to be the cause of 7%-40% of all nail dystrophies seen in children.
The most common nail findings in psoriasis are pitting, nail plate yellowing, onycholysis, subungual hyperkeratosis, splinter hemorrhages, and "oil spots." Psoriasis may also involve the nail folds in the form of swelling and chronic paronychia. Toenail findings are less frequent than psoriatic changes in the fingernails. When they do occur, subungual hyperkeratosis and yellow discoloration of the nail plate are the predominant findings.
Pediatric Patient Considerations:
Nail psoriasis in children is associated with more severe disease in most studies. It may be more common in boys than girls. The prevalence of nail psoriasis in children is 15%-19%. Furthermore, psoriasis is believed to be the cause of 7%-40% of all nail dystrophies seen in children.
Codes
ICD10CM:
L40.0 – Psoriasis vulgaris
SNOMEDCT:
9014002 – Psoriasis
L40.0 – Psoriasis vulgaris
SNOMEDCT:
9014002 – Psoriasis
Look For
Subscription Required
Diagnostic Pearls
Subscription Required
Differential Diagnosis & Pitfalls
- Onychomycosis
- Reactive arthritis (Reiter syndrome)
- Lichen planus
- Alopecia areata – Pits are generally more superficial and regular.
- Pachyonychia congenita
- Pityriasis rubra pilaris
- Idiopathic trachyonychia
- Other causes of onycholysis (eg, autoimmune diseases, medications, trauma)
- Atopic dermatitis – If there is eczema that involves the proximal nail folds, abnormalities in the nails may be seen, including coarse pits and nail dystrophy.
Best Tests
Subscription Required
Management Pearls
Subscription Required
Therapy
Subscription Required
Drug Reaction Data
Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.
Subscription Required
References
Subscription Required
Last Reviewed:05/02/2023
Last Updated:07/08/2020
Last Updated:07/08/2020

Premium Feature
VisualDx Patient Handouts
Available in the Elite package
- Improve treatment compliance
- Reduce after-hours questions
- Increase patient engagement and satisfaction
- Written in clear, easy-to-understand language. No confusing jargon.
- Available in English and Spanish
- Print out or email directly to your patient
Upgrade Today
Psoriasis - Nail and Distal Digit
See also in: Overview,Anogenital,Hair and Scalp