Calcinosis cutis in Adult
The most common clinical presentation is that of painful, irregularly surfaced nodules. In addition, extrusion of chalk-like substance from calcified nodules and secondary infection can cause pain and significant morbidity.
Dystrophic calcinosis cutis in adults is often seen in autoimmune connective tissue diseases, especially in the CREST form of systemic sclerosis, juvenile dermatomyositis, and occasionally in adult dermatomyositis (10%-20%). Less often, it can be seen in acute systemic, subacute cutaneous, and chronic cutaneous lupus erythematosus, lupus panniculitis, and generalized morphea.
The term "calcinosis universalis" has been used to describe extensive areas of cutaneous calcification with sheet-like masses of calcium deposition.
The most common cause of metastatic calcinosis cutis is advanced renal disease. Calciphylaxis, a mixed type of calcification, is the most dramatic calcification disorder that is seen primarily in chronic renal failure patients and presents as large, painful, well-demarcated violaceous plaques that evolve into necrosis. This disorder is associated with significant morbidity and mortality in this patient population.
Calcinosis cutis may occur at any age, but the increased prevalence of associated disease in the elderly population places this group at heightened risk.
L94.2 – Calcinosis cutis
21323007 – Calcinosis cutis
- Calcified epidermoid cysts
- Xanthomas (xanthoma tendinosum, xanthoma tuberosum, eruptive xanthoma)
- Molluscum contagiosum
- Osteoma cutis
- Subepidermal calcified nodule (usually solitary – head in children; extremities in adults)
- Scrotal calcinosis (often multiple)
- Pseudoxanthoma elasticum
Last Updated: 01/26/2018