Woman with Rigidity, Tremor, Bradykinesia – Let’s Diagnose

A 62-year-old woman presents to doctor with rigidity, tremor, and bradykinesia. The patient’s posture appears visibly “stooped”. When the patient walks, it is noticeable that they tend to accelerate their steps. The patient recounts that since their recent change in gait, they have been struggling to complete daily tasks due to lack of balance, and they are concerned about falling. When asked about medication history, she noted that she has been on long-term lithium therapy for management of her bipolar disorder.

Is it multiple system atrophy, parkinsonism, Huntington disease, or pantothenate  kinase-associated neurodegeneration?

Can you diagnose the patient? Use the Differential Builder in VisualDx to help you.


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